Glypican‐4 regulated actin cytoskeletal reorganization in glucocorticoid treated trabecular meshwork cells and involvement of Wnt/PCP signaling
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30953
Abstract: A common adverse response to the clinical use of glucocorticoids (GCs) is elevated intraocular pressure (IOP) which is a major risk factor for glaucoma. Elevated IOP arises due to impaired outflow of aqueous humor (AH)… read more here.
Keywords: wnt pcp; pcp signaling; pcp; trabecular meshwork ... See more keywords
IQGAP1 scaffolding links Phosphoinositide Kinases to Cytoskeletal Reorganization.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical journal"
DOI: 10.1016/j.bpj.2022.01.018
Abstract: IQGAP1 is a multi-domain scaffold protein that coordinates the direction and impact of multiple signaling pathways by scaffolding its various binding partners. However, the spatial and temporal resolution of IQGAP1 scaffolding remains unclear. Here, we… read more here.
Keywords: iqgap1 scaffolding; iqgap1; cytoskeletal reorganization; cytoskeletal changes ... See more keywords
Local mRNA translation and cytoskeletal reorganization: Mechanisms that tune neuronal responses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.949096
Abstract: Neurons are highly polarized cells with significantly long axonal and dendritic extensions that can reach distances up to hundreds of centimeters away from the cell bodies in higher vertebrates. Their successful formation, maintenance, and proper… read more here.
Keywords: mrna translation; local mrna; translation cytoskeletal; translation ... See more keywords