Extracellular calcium regulates the adhesion and migration of osteoclasts via integrin αvβ 3/Rho A/Cytoskeleton signaling
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DOI: 10.1002/cbin.11033
Abstract: Integrin αvβ3 is a transmembrane integrin, which can initiate osteoclasts’ attachment on bones, leading to downward signaling pathways and subsequent bone resorption. Different calcium concentrations have been reported to have an influence on the activation… read more here.
Keywords: cytoskeleton; extracellular calcium; adhesion migration; integrin ... See more keywords
X‐rays effects on cytoskeleton mechanics of healthy and tumor cells
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DOI: 10.1002/cm.21334
Abstract: Alterations in the cytoskeleton structure are frequently found in several diseases and particularly in cancer cells. It is also through the alterations of the cytoskeleton structure that cancer cells acquire most of their common features… read more here.
Keywords: cytoskeleton; cytoskeleton mechanics; adhesion; alterations cytoskeleton ... See more keywords
Novel approaches for imaging the cytoskeleton
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DOI: 10.1002/cm.21497
Abstract: Generations of biologists have been fascinated by the crawling, swimming, contractile, squirming, and blebbing behaviors of living cells. We now know that these dynamic processes result from the activities of the cellular cytoskeleton. Decades of… read more here.
Keywords: cytoskeleton; imaging cytoskeleton; issue; microscopy ... See more keywords
2019 Cytoskeleton Paper of the Year: A revised order of subunits in mammalian septin complexes
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DOI: 10.1002/cm.21594
Abstract: Cytoskeleton is pleased to announce the 2019 paper of the year. The paper is “A revised order of subunits in mammalian septin complexes” by Deborah C. Mendonca, Joci N. Macedo, Samuel L. Guimaraes, Fernando L.… read more here.
Keywords: cytoskeleton; septin; paper; year ... See more keywords
Actomyosin‐dependent invasion of endothelial sprouts in collagen
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DOI: 10.1002/cm.21624
Abstract: During sprouting angiogenesis—the growth of blood vessels from the existing vasculature—endothelial cells (ECs) adopt an elongated invasive form and exert forces at cell–cell and cell–matrix interaction sites. These cell shape changes and cellular tractions require… read more here.
Keywords: cytoskeleton; invasion endothelial; sprouts collagen; dependent invasion ... See more keywords
Structural change and degradation of cytoskeleton due to the acrolein conjugation with vimentin and actin during brain infarction
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DOI: 10.1002/cm.21638
Abstract: We have found recently that dendritic spine extension is inhibited through acrolein conjugation with α‐ and β‐tubulin proteins during brain infarction. In this current study, we looked for other acrolein‐conjugated proteins in the 100,000g precipitate… read more here.
Keywords: cytoskeleton; vimentin; actin; brain infarction ... See more keywords
miR96- and miR182-driven regulation of cytoskeleton results in inhibition of glioblastoma motility.
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DOI: 10.1002/cm.21754
Abstract: Glioblastoma multiforme (GBM) is one of the most common forms of brain tumors. As an excessively invasive tumor type, GBM cannot be fully cured due to its invasion ability into the healthy brain tissues. Therefore,… read more here.
Keywords: gbm; motility; spastin palladin; mir96 mir182 ... See more keywords
IL‐6 increases podocyte motility via MLC‐mediated focal adhesion impairment and cytoskeleton disassembly
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DOI: 10.1002/jcp.26546
Abstract: The disturbance of podocyte motility is an essential pathogenic mechanisms of foot process effacement during proteinuric diseases, and myosin light chain (MLC) is a pivotal component in regulating the motility of podocytes. Inflammatory cytokine interleukin‐6… read more here.
Keywords: cytoskeleton; focal adhesion; motility; mlc ... See more keywords
Regulation of PIEZO1 channels by lipids and the structural components of extracellular matrix/cell cytoskeleton
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DOI: 10.1002/jcp.31001
Abstract: PIEZO1 is a mechanosensitive channel widely presented in eukaryotic organisms. Although the PIEZO family was discovered in 2010, main questions related to the molecular structure as well as to specific activation mechanisms and regulating pathways… read more here.
Keywords: extracellular matrix; components extracellular; cytoskeleton; regulation piezo1 ... See more keywords
Artificial Cytoskeleton Assembly for Synthetic Cell Motility.
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DOI: 10.1002/mabi.202200437
Abstract: Imitation of cellular processes in cell-like compartments is a current research focus in synthetic biology. Here, we introduce a method for assembling an artificial cytoskeleton in a synthetic cell model system based on a poly(N-isopropylacrylamide)… read more here.
Keywords: synthetic cell; artificial cytoskeleton; cytoskeleton; biology ... See more keywords
Association Between Functional Activity of Mitochondria and Actin Cytoskeleton Instability in Oocytes from Advanced Age Mice
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DOI: 10.1007/s43032-020-00145-2
Abstract: Mitochondrial dysfunction is strongly associated with the oocyte quality and aging, wherein the aged oocytes are related to the actin cytoskeleton integrity; however, whether this integrity is associated with mitochondrial dysfunction in oocytes from aged… read more here.
Keywords: cytoskeleton; actin cytoskeleton; aged oocytes; cytoskeleton instability ... See more keywords