Molecular characterization of a cytosolic malate dehydrogenase gene(GhcMDH1) from cotton
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-017-6358-9
Abstract: Malate dehydrogenase(MDH) is a key enzyme that catalyzes the reversible oxidation of oxaloacetate to malate and plays an important role in the physiological processes of plant growth and development. However, cyto-solic malate dehydrogenase(cMDH), which is… read more here.
Keywords: cotton; malate; cytosolic malate; gene ... See more keywords
Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2017.36
Abstract: Increased glucose consumption is a hallmark of cancer cells. The increased consumption and subsequent metabolism of glucose during proliferation creates the need for a constant supply of NAD, a co-factor in glycolysis. Regeneration of the… read more here.
Keywords: glycolysis; cytosolic malate; proliferating cells; cancer ... See more keywords
Thermal Adaptation of Cytosolic Malate Dehydrogenase Revealed by Deep Learning and Coevolutionary Analysis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Chemical Theory and Computation"
DOI: 10.1101/2024.10.08.617074
Abstract: Protein evolution has produced enzymes that maintain stability and function across various thermal environments. While sequence variation, structural dynamics, and intermolecular interactions are known to influence an enzyme’s thermal adaptation, how these factors collectively govern… read more here.
Keywords: deep learning; adaptation; stability; cytosolic malate ... See more keywords