Pathomechanisms of anti–cytosolic 5′‐nucleotidase 1A autoantibodies in sporadic inclusion body myositis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.24919
Abstract: Sporadic inclusion body myositis (sIBM), an intractable progressive muscle disease, frequently occurs in older persons. sIBM pathogenesis may involve protein degradation dysfunction and immune abnormalities. Autoantibodies recognizing cytosolic 5′‐nucleotidase 1A (cN1A) were found in plasma… read more here.
Keywords: body myositis; cytosolic nucleotidase; sporadic inclusion; inclusion body ... See more keywords
The cytosolic 5'-nucleotidase cN-II lowers the adaptability to glucose deprivation in human breast cancer cells.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18653
Abstract: The cytosolic 5'-nucleotidase cN-II is a highly conserved enzyme implicated in nucleotide metabolism. Based on recent observations suggesting additional roles not directly associated to its enzymatic activity, we studied human cancer cell models with basal… read more here.
Keywords: glucose deprivation; cancer cells; expression; cytosolic nucleotidase ... See more keywords