Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway.
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DOI: 10.1016/j.celrep.2017.04.063
Abstract: Intestinal epithelial cells (IECs) act as sentinels for incoming pathogens. Cytosol-invasive bacteria, such as Shigella flexneri, trigger a robust pro-inflammatory nuclear factor κB (NF-κB) response from IECs that is believed to depend entirely on the… read more here.
Keywords: surveillance pathway; tifa dependent; cytosolic surveillance; dependent cytosolic ... See more keywords