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Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2232-z
Abstract: Five nitrofuroxans were synthesized and evaluated for their in vitro cytotoxicity against human lymphoma cells with different p53 status (Raji Burkitt's lymphoma and MOLT-4). The most promising compound exhibited IC50 values of 2.6–11.0 μM in…
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Keywords:
activity nitrofuroxans;
microscopy;
lymphoma cells;
nitrofuroxans lymphoma ... See more keywords
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Published in 2022 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520623666221116110823
Abstract: BACKGROUND Many ceramidase inhibitors have been developed and identified as potential treatment agents for various types of tumors in the last several decades. In recent years, their therapeutic potential against tumors has gained great attention.…
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Keywords:
apoptosis;
264 macrophage;
ceranib;
cytotoxic apoptotic ... See more keywords