LC-MS identification and cytotoxic assessment of jaspamide and its congeners from the sponge jaspis diastra
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DOI: 10.1039/d3nj00459g
Abstract: Jaspamide (jasplakinolide; NSC-613009) is a cytotoxic cyclic polypeptide that was initially isolated from the sponge Jaspis cf. Johnston. It displayed anti-tumor, anti-fungal and insecticidal activities, among others. Herein, an LC-MS/MS... read more here.
Keywords: jaspamide; sponge jaspis; identification cytotoxic; assessment jaspamide ... See more keywords
Cytotoxic Assessment of 3,3-Dichloro-β-Lactams Prepared through Microwave-Assisted Benzylic C-H Activation from Benzyl-Tethered Trichloroacetamides Catalyzed by RuCl2(PPh3)3
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DOI: 10.3390/molecules27185975
Abstract: Natural and synthetic β-lactam derivatives constitute an interesting class of compounds due to their diverse biological activity. Mostly used as antibiotics, they were also found to have antitubercular, anticancer and antidiabetic activities, among others. In… read more here.
Keywords: cytotoxic assessment; assessment dichloro; prepared microwave; dichloro lactams ... See more keywords