Abstract LB-B11: Myeloid p38 MAPK promotes tumorigenesis by suppressing cytotoxic T cell recruitment
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-lb-b11
Abstract: The last decade has seen explosive progress in understanding how tumor-associated macrophages (TAM) contribute to the development, metastasis, and therapy resistance of cancer. TAM and their molecular components are investigated as targets for cancer therapy.… read more here.
Keywords: expression; p38; cancer; cell recruitment ... See more keywords
T cells presenting viral antigens or autoantigens induce cytotoxic T cell anergy.
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DOI: 10.1172/jci.insight.96173
Abstract: In the course of modeling the naturally occurring tumor immunity seen in patients with paraneoplastic cerebellar degeneration (PCD), we discovered an unexpectedly high threshold for breaking CD8+ cytotoxic T cell (CTL) tolerance to the PCD… read more here.
Keywords: cells presenting; presenting viral; cytotoxic cell; flu ... See more keywords
Cytotoxic T-Cell-Based Vaccine against SARS-CoV-2: A Hybrid Immunoinformatic Approach
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DOI: 10.3390/vaccines10020218
Abstract: This paper presents an alternative vaccination platform that provides long-term cellular immune protection mediated by cytotoxic T-cells. The immune response via cellular immunity creates superior resistance to viral mutations, which are currently the greatest threat… read more here.
Keywords: class; class class; cell based; cytotoxic cell ... See more keywords