Synthesis, cytotoxic characterization, and SAR study of imidazo[1,2‐b]pyrazole‐7‐carboxamides
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DOI: 10.1002/ardp.201800062
Abstract: The synthesis and in vitro cytotoxic characteristics of new imidazo[1,2‐b]pyrazole‐7‐carboxamides were investigated. Following a hit‐to‐lead optimization exploiting 2D and 3D cultures of MCF‐7 human breast, 4T1 mammary gland, and HL‐60 human promyelocytic leukemia cancer cell… read more here.
Keywords: pyrazole carboxamides; cytotoxic characterization; imidazo pyrazole; sar ... See more keywords