Genome Mining and Metabolic Profiling Reveal Cytotoxic Cyclodipeptides in Streptomyces hygrospinosus var. Beijingensis
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DOI: 10.3390/antibiotics11111463
Abstract: Two new cyclodipeptide (CDP) derivatives (1–2) and another seven known cyclodipeptides (3–9) were isolated from Streptomyces 26D9-414 by the genome mining approach combined with genetic dereplication and the “one strain many compounds” (OSMAC) strategy. The… read more here.
Keywords: reveal cytotoxic; profiling reveal; genome mining; cytotoxic cyclodipeptides ... See more keywords