Chemotherapeutic dosing implicated by pharmacodynamic modeling of in vitro cytotoxic data: a case study of paclitaxel
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DOI: 10.1007/s10928-017-9540-2
Abstract: Conventional maximum tolerated doses (MTD) in chemotherapy are recently challenged by an alternative dosing method with low doses and high dosing frequency (LDHF). Still, it remains unclear which chemotherapies would potentially benefit from LDHF. The… read more here.
Keywords: chemotherapeutic dosing; cytotoxic; model; cytotoxic data ... See more keywords