Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society transactions"
DOI: 10.1042/bst20221409
Abstract: ABC toxins are pore-forming toxins characterised by the presence of three distinct components assembled into a hetero-oligomeric toxin complex ranging in size from 1.5-2.5 MDa. Most ABC toxins studied to date appear to be insecticidal toxins,… read more here.
Keywords: abc toxins; pore forming; cell; forming toxins ... See more keywords
A Ménage à Trois of Cytotoxic Effector Cells: γδ T Cells Suppress NK Cells but Not CTLs.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-22-0148
Abstract: Three types of cytotoxic effector cells can kill tumor cells: innate natural killer (NK) cells, CD8+ CTL, and γδ T cells. In this issue, Walwyn-Brown and colleagues report new insights into the interplay between these… read more here.
Keywords: nage trois; suppress cells; trois cytotoxic; cytotoxic effector ... See more keywords
Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1058267
Abstract: The T-box transcription factors T-bet and Eomesodermin regulate type 1 immune responses in innate and adaptive lymphocytes. T-bet is widely expressed in the immune system but was initially identified as the lineage-specifying transcription factor of… read more here.
Keywords: eomes sufficient; cd4; cd4 cells; expression ... See more keywords