Articles with "cytotoxic effects" as a keyword



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Gold nanoparticles regulate the antitumor secretome and have potent cytotoxic effects against prostate cancer cells

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Published in 2020 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.4117

Abstract: The specific cytotoxic effects of nanoparticles on tumor cells may be used in future antitumor clinical applications. Gold nanoparticles (AuNPs) have been reported to produce potent cytotoxic effects; however, the precise mechanism is unclear. In… read more here.

Keywords: cytotoxic effects; microscopy; prostate cancer; cancer cells ... See more keywords
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Cytotoxic effects of Satureja montana L. essential oil on oocytes of engorged Rhipicephalus microplus female ticks (Acari: Ixodidae)

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Published in 2021 at "Microscopy Research and Technique"

DOI: 10.1002/jemt.23693

Abstract: In addition to pesticidal activity, the capacity of natural compounds to inhibit the reproduction of parasites emerge as an important alternative tick control method. In this context, Satureja spp. stand out due to their recognized… read more here.

Keywords: essential oil; rhipicephalus microplus; cytotoxic effects; effects satureja ... See more keywords
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Assessment of the cytotoxic effects of aporphine prototypes on head and neck cancer cells

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Published in 2019 at "Investigational New Drugs"

DOI: 10.1007/s10637-019-00784-6

Abstract: Purpose Among alkaloids, abundant secondary metabolites in plants, aporphines constitute a class of compounds with interesting biological activities, including anticancer effects. The present study evaluated the anticancer activities of 14 substances, including four aporphine derivatives… read more here.

Keywords: neck cancer; cytotoxic effects; cancer cells; cell ... See more keywords
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The Comparative Cytotoxic Effects of Apis mellifera Crude Venom on MCF-7 Breast Cancer Cell Line in 2D and 3D Cell Cultures

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Published in 2019 at "International Journal of Peptide Research and Therapeutics"

DOI: 10.1007/s10989-019-09979-0

Abstract: Bee venom (BV) has variety of properties, such as anti-inflammatory potential and anti-cancer activity.It has been shown that BV has cytotoxic effects on MCF-7 cells in 2D culture. Cell encapsulation is one of the three-dimensional… read more here.

Keywords: cytotoxic effects; mcf cells; venom; culture ... See more keywords
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Cytotoxic effects, microbiological analysis and inhibitory properties on carbonic anhydrase isozyme activities of 2-hydroxy-5-methoxyacetophenone thiosemicarbazone and its Cu(II), Co(II), Zn(II) and Mn(II) complexes

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Published in 2020 at "Research on Chemical Intermediates"

DOI: 10.1007/s11164-020-04284-8

Abstract: Metal complexes of thiosemicarbazones have been receiving considerable attention in biological applications such as antimicrobial and anticancer therapies. In this work, Co(II), Zn(II) and Mn(II) complexes of 2-hydroxy-5-methoxyacetophenone thiosemicarbazone (HMAT) were synthesized for the first… read more here.

Keywords: carbonic anhydrase; cytotoxic effects; analysis; microbiological analysis ... See more keywords
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Evaluation of textile laundry effluents and their cytotoxic effects on Allium cepa

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Published in 2018 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-018-2813-5

Abstract: Industrial laundries have water as one of their main inputs and they release effluents in large amounts, with a high polluting load, which are usually discarded into the environment, or they are insufficiently treated for… read more here.

Keywords: allium cepa; laundry; cytotoxic effects; evaluation ... See more keywords
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Cyr61 Alleviates Cholangitis by Inhibiting Cytotoxic Effects of CD8+ T Cells on Biliary Epithelial Cells

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Published in 2021 at "Current Medical Science"

DOI: 10.1007/s11596-021-2458-3

Abstract: Primary biliary cholangitis (PBC) is a chronic progressive cholestatic liver disease. In recent years, researchers have found that cysteine-rich angiogenic inducer 61 (Cyr61, also known as CCN1) has a potential role in reducing portal inflammation… read more here.

Keywords: epithelial cells; cytotoxic effects; pbc; cd8 cells ... See more keywords
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Comparison of the Physical Characteristics of Green-Synthesized and Commercial Silver Nanoparticles: Evaluation of Antimicrobial and Cytotoxic Effects

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Published in 2017 at "Arabian Journal for Science and Engineering"

DOI: 10.1007/s13369-016-2254-8

Abstract: We investigated a novel green route synthesis of silver nanoparticles (AgNPs) using watermelon rind powder extract (WR-AgNPs) as a reducing and capping agent. The efficiency of nanoparticle synthesis was evaluated by comparing the structure, functional… read more here.

Keywords: silver nanoparticles; cytotoxic effects; synthesized commercial; spectroscopy ... See more keywords
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Relation between structures of naphthalenylchalcone derivatives and their cytotoxic effects on HCT116 human colon cancer cells

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Published in 2018 at "Applied Biological Chemistry"

DOI: 10.1007/s13765-018-0356-6

Abstract: To find potent chemotherapeutic agents, cytotoxic effects of 42 synthetic chalcone derivatives bearing naphthyl groups on HCT116 human colon cancer cell lines were tested using the clonogenic long-term survival assay. The relationships between their half-maximal… read more here.

Keywords: cytotoxic effects; hct116 human; human colon; colon cancer ... See more keywords
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Novel nitroaromatic compound activates autophagy and apoptosis pathways in HL60 cells.

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Published in 2018 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2017.12.012

Abstract: N-(2-butanoyloxyethyl)-4-(chloromethyl)-3-nitrobenzamide (NBCN) is a nitroaromatic bioreducible compound with cytotoxic effects in cancer cell lines. The aim of this work was to investigate the molecular mechanisms involved in cell death promoted by NBCN in HL60 cells.… read more here.

Keywords: nitroaromatic compound; cytotoxic effects; compound activates; novel nitroaromatic ... See more keywords
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The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis.

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Published in 2020 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2020.109334

Abstract: The cytotoxic potential of a naturally occurring indoloquinazoline alkaloid, soyauxinium chloride (SCHL), was determined on a broad panel of animal and human cancer cell lines, including various sensitive and drug-resistant phenotypes. The cytotoxicity, SCHL-induced autophagic,… read more here.

Keywords: cytotoxic effects; alkaloid soyauxinium; apoptosis; soyauxinium chloride ... See more keywords