Assessment of the cytotoxic, genotoxic, and apoptotic potential of flurbiprofen in HeLa and HepG2 cell lines
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22770
Abstract: In the literature, the anticancer potential of flurbiprofen isn't fully understood. In this study, the cytotoxic, genotoxic, and apoptotic effects of flurbiprofen were evaluated in human cervical and liver cancer cells. Cytotoxicity was measured by… read more here.
Keywords: cell; genotoxic apoptotic; potential flurbiprofen; cytotoxic genotoxic ... See more keywords
Treated Textile Effluents: Cytotoxic and Genotoxic Effects in the Natural Aquatic Environment
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Environmental Contamination and Toxicology"
DOI: 10.1007/s00128-019-02768-x
Abstract: Textile effluent treatment methods use biological and chemical treatments to reduce the toxicity and to comply with standard effluent discharge limits. However, trace amounts of pollutants can affect the biological organisms in the receiving environment.… read more here.
Keywords: textile effluents; treated textile; genotoxic effects; environment ... See more keywords
Assessment of in vitro cytotoxic and genotoxic activities of some trimethoprim conjugates
Sign Up to like & getrecommendations! Published in 2018 at "Cytotechnology"
DOI: 10.1007/s10616-018-0187-7
Abstract: Trimethoprim, a commonly used antibacterial agent, is widely applied in the treatment of variety of infections in human. A few studies have demonstrated an extensive exposure of man to antibiotics, but there is still a… read more here.
Keywords: cytotoxic; activities trimethoprim; genotoxic activities; assessment vitro ... See more keywords
Hydropower reservoirs: cytotoxic and genotoxic assessment using the Allium cepa root model
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-8509-4
Abstract: Hydropower offers a reliable source of electricity in several countries, and Brazil supplies its energy needs almost entirely through hydropower plants. Nevertheless, hydropower plants comprise large buildings and water reservoirs and dams, resulting in huge… read more here.
Keywords: cytotoxic genotoxic; allium cepa; hydropower reservoirs; hydropower ... See more keywords
Cytotoxic, genotoxic and mutagenic evaluation of surface waters from a coal exploration region.
Sign Up to like & getrecommendations! Published in 2017 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.01.024
Abstract: Coal mining generates a considerable amount of waste, which is disposed of in piles or dams near mining sites. As a result, leachates may reach rivers and streams, promoting the wide dispersion of contaminants in… read more here.
Keywords: surface waters; genotoxic mutagenic; water samples; cytotoxic genotoxic ... See more keywords
Monitoring of morphotoxic, cytotoxic and genotoxic potential of mancozeb using Allium assay.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.12.052
Abstract: The present experiment was designed to monitor the morphotoxic, cytotoxic and genotoxic potential of Mancozeb (fungicide) in non-target plants using bulbs of Allium cepa. Mancozeb is classified as a contact fungicide and is registered for… read more here.
Keywords: morphotoxic cytotoxic; cytotoxic; genotoxic potential; mancozeb ... See more keywords
Cytotoxic and genotoxic effects of epoxiconazole on F98 glioma cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.05.018
Abstract: Epoxiconazole (EPX) is a very effective fungicide of the triazole family. Given its wide spectrum of use, the increased application of this pesticide may represent a serious risk on human health. Previous studies have found… read more here.
Keywords: effects epoxiconazole; f98 glioma; genotoxic effects; epx ... See more keywords
Novel nitroimidazole derivatives evaluated for their trypanocidal, cytotoxic, and genotoxic activities.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111887
Abstract: The current treatment of Chagas disease is based on the use of two drugs, nifurtimox (Nfx) and benznidazole (Bnz), both of which present limited efficacy in the chronic stage of the disease and toxic side… read more here.
Keywords: nitroimidazole derivatives; genotoxic activities; derivatives evaluated; novel nitroimidazole ... See more keywords
Cytotoxic and genotoxic effects of antihypertensives distributed in Brazil by social programs: Are they safe?
Sign Up to like & getrecommendations! Published in 2018 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2018.08.005
Abstract: Hypertension, a chronic non-transmissible multifactorial condition, it is highly frequent in Brazil, affecting about 32.5% of the population over 25 years of age. It is characterized by the sustained increase in systolic and diastolic blood… read more here.
Keywords: dna damage; dna; captopril enalapril; genotoxic effects ... See more keywords
Chemical characterization and cytotoxic, genotoxic, and mutagenic properties of Baccharis trinervis (Lam, Persoon) from Colombia and Brazil.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.10.027
Abstract: PHARMACOLOGY RELEVANCE Baccharis trinervis (Lam, Persoon) leaves are used in the traditional medicine for the treatment of high fevers, edema, inflammation, sores and muscle cramps, snakebites and as antiseptic. AIM OF THE STUDY To investigate… read more here.
Keywords: genotoxic mutagenic; colombia; mutagenic effects; cytotoxic genotoxic ... See more keywords
The potential of geraniol to reduce cytotoxic and genotoxic effects of MNNG in plant and human lymphocyte test-systems
Sign Up to like & getrecommendations! Published in 2019 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2019.03.005
Abstract: Abstract Geraniol is a common component of essential oils of various plant species and is widely used in cosmetics, perfumery and household products. In the present study, we investigated the cytotoxic, genotoxic and antioxidant activities… read more here.
Keywords: test systems; cytotoxic genotoxic; genotoxic effects; genotoxic ... See more keywords