Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells
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DOI: 10.1371/journal.ppat.1010034
Abstract: Siglec-9 is an MHC-independent inhibitory receptor expressed on a subset of natural killer (NK) cells. Siglec-9 restrains NK cytotoxicity by binding to sialoglycans (sialic acid-containing glycans) on target cells. Despite the importance of Siglec-9 interactions… read more here.
Keywords: siglec; hiv infected; highly cytotoxic; cytotoxic hiv ... See more keywords