Optimal control of a delayed hepatitis B viral infection model with cytotoxic T-lymphocyte and antibody responses
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Dynamics and Control"
DOI: 10.1007/s40435-016-0231-4
Abstract: The dynamics of a model describing the hepatitis B viral infection model with cytotoxic T-lymphocyte and antibody responses is studied in this paper. The model consists of a system of differential equations describing the interaction… read more here.
Keywords: hepatitis viral; infection model; cytotoxic lymphocyte; model ... See more keywords
Injectable polypeptide hydrogel for dual-delivery of antigen and TLR3 agonist to modulate dendritic cells in vivo and enhance potent cytotoxic T-lymphocyte response against melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.01.004
Abstract: Transplantation of immune cells manipulated in vitro to dictate immune responses in the body is promising in cancer immunotherapy. However, this approach suffers from low cell survival after administration, insufficient cell homing to lymph nodes, and… read more here.
Keywords: tlr3 agonist; hydrogel; polypeptide hydrogel; delivery ... See more keywords
Cytotoxic T Lymphocyte Granzyme-b mediates neuronal cell death during Plasmodium berghei ANKA induced experimental cerebral malaria
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.11.021
Abstract: Cerebral malaria is a complex, acute, neurological disease characterised by a sudden onset of cerebral symptoms. This disease is manifested as initial arousable stage that is followed by an unarousable coma and eventually death. Parasite… read more here.
Keywords: death; cytotoxic lymphocyte; granzyme; experimental cerebral ... See more keywords
Association between SNPs of Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death 1 (PD-1)and the susceptibility to chronic Hepatitis C infection in virus C-infected patients.
Sign Up to like & getrecommendations! Published in 2022 at "Virus research"
DOI: 10.1016/j.virusres.2022.198684
Abstract: BACKGROUND Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1) are immune inhibitory factors that provide inhibitory signals to T cells. METHODS A case-controlled genetic association study was conducted in478 patients (160 patients… read more here.
Keywords: hcv; cytotoxic lymphocyte; infection; virus ... See more keywords
Associations between cytotoxic T-lymphocyte-associated antigen 4 gene polymorphisms and diabetes mellitus: a meta-analysis of 76 case–control studies
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DOI: 10.1042/bsr20190309
Abstract: Background: Several genetic association studies already investigated potential roles of cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) gene polymorphisms in diabetes mellitus (DM), with inconsistent results. Therefore, we performed this meta-analysis to better assess the relationship between… read more here.
Keywords: cytotoxic lymphocyte; gene polymorphisms; associated antigen; diabetes mellitus ... See more keywords
Cytotoxic T-lymphocyte elicited therapeutic vaccine candidate targeting cancer against MAGE-A11 carcinogenic protein
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DOI: 10.1042/bsr20202349
Abstract: Abstract Immunotherapy is a breakthrough approach for cancer treatment and prevention. By exploiting the fact that cancer cells have overexpression of tumor antigens responsible for its growth and progression, which can be identified and removed… read more here.
Keywords: cytotoxic lymphocyte; androgen receptor; cancer; epitope ... See more keywords
Cytotoxic T-lymphocyte-associated protein 4 gene polymorphism is related to rheumatoid arthritis in Egyptian population
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Physiology and Biochemistry"
DOI: 10.1080/13813455.2016.1230135
Abstract: Abstract Context: Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a CD28-family receptor expressed on T-cells which suppresses T cell proliferation. CTLA-4 -318C/T polymorphism is involved in regulation of CTLA-4 expression. Objective: The study aimed to investigate… read more here.
Keywords: associated protein; polymorphism; ctla; cytotoxic lymphocyte ... See more keywords
Association of cytotoxic T-lymphocyte antigen-4 (CTLA-4) single nucleotide polymorphism in donors with clinical outcome after allogeneic hematopoietic stem cell transplantation: a meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Hematology"
DOI: 10.1080/16078454.2020.1852762
Abstract: OBJECTIVE Cytotoxic T-lymphocyte antigen 4 (CTLA-4) polymorphisms at positions of +49 and CT60 in donors have been reported to influence clinical outcome following allogeneic hematopoietic stem cell transplantation (allo-HSCT), such as overall survival (OS), disease… read more here.
Keywords: outcome; ctla; cytotoxic lymphocyte; polymorphism ... See more keywords
P12.06 Clinicopathological evaluation of PD-L1 expression and cytotoxic T-lymphocyte infiltrates across intracranial molecular subgroups of ependymomas
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DOI: 10.1093/neuonc/noz126.217
Abstract: Immune check-point blockade targeting programmed cell death ligand-1 (PD-L1)/programmed death-1 (PD-1) axis has created paradigm shift in the treatment of advanced cancer. The prognosis of the ‘ST-RELA’ and ‘PF-A’ molecular subgroups of ependymomas (EPN) remains… read more here.
Keywords: rela; molecular subgroups; subgroups ependymomas; epns ... See more keywords
High cytotoxic T-lymphocyte-associated antigen 4 and phospho-Akt expression in tumor samples predicts poor clinical outcomes in ipilimumab-treated melanoma patients
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DOI: 10.1097/cmr.0000000000000305
Abstract: Ipilimumab, a fully human monoclonal antibody against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), is the first immune checkpoint inhibitor approved for the treatment of unresectable melanoma on the basis of its overall survival (OS) benefit. However,… read more here.
Keywords: tumor samples; cytotoxic lymphocyte; akt expression; expression ... See more keywords
Alloreactive cytotoxic T lymphocyte immunotherapy treatment of a patient with metastatic prostate cancer
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DOI: 10.1097/md.0000000000011111
Abstract: Rationale: Cytotoxic T lymphocyte (CTL) immunotherapy is an autologous cellular immune therapy that has been approved for treating patients with malignant tumors. However, there is still limited information regarding the impact of CTL on metastatic… read more here.
Keywords: prostate; metastatic prostate; treatment; cytotoxic lymphocyte ... See more keywords