Isolation and characterization of cytotoxic withanolides from the calyx of Physalis alkekengi L. var franchetii.
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DOI: 10.1016/j.bioorg.2020.103614
Abstract: Phytochemical investigation into the calyx of Physalis alkekengi L. var franchetii (Mast) Makino resulted in the isolation of ten cytotoxic withanolides, including five new withanolides, 1-5. Compounds 2-4 were obtained as epimeric withaphysalins. The new… read more here.
Keywords: cytotoxic withanolides; cytotoxic; calyx physalis; physalis alkekengi ... See more keywords
Target discovery of cytotoxic withanolides from Physalis angulata var. villosa via reactivity‐based screening
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DOI: 10.1016/j.jpba.2017.12.047
Abstract: Graphical abstract Figure. No caption available. HighlightsThe reactivity‐based screening (RBS) approach was developed.Thiol probe targeted withanolides via the nucleophilic addition to 2(3)‐en‐1‐one.Eleven cytotoxic withanolides were discovered from plant extract directed by RBS. ABSTRACT The reactivity‐based… read more here.
Keywords: cytotoxic withanolides; discovery cytotoxic; cytotoxic; reactivity based ... See more keywords
Cytotoxic withanolides from Physalis angulata
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DOI: 10.1080/14786419.2017.1338281
Abstract: Abstract A new withanolide (1), physagulide P, together with five known withanolides (2–6), was isolated from the aerial parts of Physalis angulata L. The structure of new compound was elucidated on the basis of extensive… read more here.
Keywords: physalis angulata; cytotoxic withanolides; withanolides physalis;