Synthesis of some steroidal mitocans of nanomolar cytotoxicity acting by apoptosis.
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DOI: 10.1016/j.ejmech.2020.112425
Abstract: Several steroids (abiraterone, prednisone, testosterone, cholesterol) and the BCL-2 inhibitor bexarotene were used as starting materials to synthesize iperazinyl-spacered rhodamine B conjugates. The conjugates were screened for their cytotoxicity in SRB assays against several human… read more here.
Keywords: cytotoxicity acting; mitocans nanomolar; steroidal mitocans; synthesis steroidal ... See more keywords