Approaches to repurposing reverse transcriptase antivirals in cancer
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DOI: 10.1002/bcp.70113
Abstract: This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.… read more here.
Keywords: cytotoxicity cancer; cell; transcriptase; reverse transcriptase ... See more keywords
Integrating In Silico and In Vitro Approaches to Identify Natural Peptides with Selective Cytotoxicity against Cancer Cells
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DOI: 10.3390/ijms25136848
Abstract: Anticancer peptides (ACPs) are bioactive compounds known for their selective cytotoxicity against tumor cells via various mechanisms. Recent studies have demonstrated that in silico machine learning methods are effective in predicting peptides with anticancer activity.… read more here.
Keywords: cytotoxicity cancer; cytotoxicity; anticancer; peptides selective ... See more keywords