Synthesis, characterization, cytotoxicity, DNA binding and computational studies of an anionic palladium(II) complex derived from 8-hydroxyquinoline and 1,1-cyclobutanedicarboxylate
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DOI: 10.1007/s13738-017-1269-8
Abstract: A novel 1,1-cyclobutanedicarboxylato-8-hydroxyquinolinatopalladate(II), Na[Pd(8-QO)(cbdca)] (8-QO = 8-hydroxyquinoline and cbdca = 1,1-cyclobutanedicarboxylate) has been designed and synthesized. The structure of the complex has been characterized by elemental analysis, molar conductance, FT-IR, UV–Vis, 13C NMR, 1H NMR spectroscopy. The cytotoxic activities… read more here.
Keywords: cyclobutanedicarboxylate; cytotoxicity dna; characterization cytotoxicity; spectroscopy ... See more keywords
5-Lipoxygenase Contributes to Benzo[a]pyrene-Induced Cytotoxicity and DNA Damage in Human Bronchial Epithelial Cells
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DOI: 10.1177/10915818221146286
Abstract: Metabolic activation of indirect-acting carcinogens in target organs is a recognized mechanism of carcinogenesis. This study aimed to determine the role of benzo[a]pyrene (BaP) metabolism enzymes lipoxygenase (LOX), cytochrome P4501A1 (CYP1A1), and prostaglandin synthetase (PGS)… read more here.
Keywords: cytotoxicity dna; bap; cytotoxicity; dna damage ... See more keywords