Articles with "cytotoxicity evaluation" as a keyword



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Synthesis and cytotoxicity evaluation of olivacine-indole hybrids tethered by alkyl linkers.

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Published in 2021 at "Natural product research"

DOI: 10.1080/14786419.2021.1880401

Abstract: In this work, eleven new derivatives were prepared of the alkaloid olivacine (1), which was isolated from the bark of Aspidosperma australe. These compounds (7a-k) are hybrids of olivacine and indoles or carbazole, tethered by… read more here.

Keywords: olivacine; synthesis cytotoxicity; evaluation olivacine; cytotoxicity evaluation ... See more keywords
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Synthesis, cytotoxicity evaluation, and molecular modeling studies of 2,N10-substituted acridones as DNA-intercalating agents

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Published in 2020 at "Journal of Chemical Research"

DOI: 10.1177/1747519820902674

Abstract: Acridine-based compounds possess anticancer activities by intercalating to DNA. Although they have chemotherapeutic potential, acridine-based compounds are not used to treat cancer. In this study, 2,N10-acridone derivatives are designed and synthesized based on acridone, a… read more here.

Keywords: synthesis cytotoxicity; molecular modeling; modeling studies; cytotoxicity evaluation ... See more keywords
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Synthesis, Cytotoxicity Evaluation and Molecular Docking Studyof N-Phenylpyrazoline Derivatives

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Published in 2019 at "Indonesian Journal of Chemistry"

DOI: 10.22146/ijc.45777

Abstract: The synthesis of N-phenylpyrazolines 1-5 was performed by the cyclocondensation of phenylhydrazine and appropriate chalcones that have been synthesized from our previous work. All of the compounds were elucidated for their structure using GC-MS, FTIR,… read more here.

Keywords: cell line; cytotoxicity evaluation; synthesis cytotoxicity; cell ... See more keywords
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One-Pot Hydrothermal Preparation of Hydroxyapatite/Zinc Oxide Nanorod Nanocomposites and Their Cytotoxicity Evaluation against MG-63 Osteoblast-like Cells

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28010345

Abstract: In the present study, HAp-ZnO nanorod nanocomposites were successfully prepared using a customized hydrothermal reactor and studied for their compatibility against MG-63 osteoblast-like cells. The crystallinity, morphology, presence of chemical elements, and surface area properties… read more here.

Keywords: osteoblast like; microscopy; nanorod nanocomposites; cytotoxicity evaluation ... See more keywords
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Formulation, Characterization, and Cytotoxicity Evaluation of Lactoferrin Functionalized Lipid Nanoparticles for Riluzole Delivery to the Brain

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14010185

Abstract: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a very poor prognosis. Its treatment is hindered by a lack of new therapeutic alternatives and the existence of the blood–brain barrier (BBB), which restricts the… read more here.

Keywords: brain; lactoferrin; cytotoxicity evaluation; formulation characterization ... See more keywords
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Cytotoxicity Evaluation and Antioxidant Activity of a Novel Drink Based on Roasted Avocado Seed Powder

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Published in 2022 at "Plants"

DOI: 10.3390/plants11081083

Abstract: The avocado seed is an underused waste resulting from the processing of pulp. Polyphenols, fibers, and carotenoids are present in the seed, which also exhibits prophylactic, fungicidal, and larvicidal effects. Developing food products with avocado… read more here.

Keywords: avocado seed; novel drink; cytotoxicity evaluation; activity ... See more keywords
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Cytotoxicity evaluation of a new ozonized olive oil

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Published in 2018 at "European Journal of Dentistry"

DOI: 10.4103/ejd.ejd_422_18

Abstract: Objective: The cytocompatibility of a new ozonized olive oil toward immortalized human gingival fibroblasts (HGFs) was evaluated and compared with two common antimicrobial agents based on chlorhexidine digluconate (CHX). Materials and Methods: The cytocompatibility of… read more here.

Keywords: cytotoxicity evaluation; evaluation new; new ozonized; ozonized olive ... See more keywords