Ion exchange resin-catalyzed synthesis of bridged tetraoxanes possessing in vitro cytotoxicity against HeLa cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-020-02722-4
Abstract: Bridged 1,2,4,5-tetraoxanes were prepared using available acidic ion exchange resin with high yields despite the possibility of peroxide decomposition under heterogeneous conditions. The bridged tetraoxanes demonstrated high cytotoxicity against HeLa cancer cells in vitro, which… read more here.
Keywords: cytotoxicity hela; exchange resin; ion exchange; cancer cells ... See more keywords
Synthesis of 4-hetero-16α,17α-cyclohexanopregnanes and evaluation of their cytotoxicity against the HeLa cell line
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DOI: 10.1007/s11172-018-2336-8
Abstract: The oxidation of the ring A of 16α,17α-cyclohexanoprogesterone gave 5-oxo-A-nor-3,5-secopregnan-3-oic acid. The subsequent ring A closure in the latter compound upon treatment with sodium acetate in Ac2O afforded 4-oxasteroid. The reaction with ammonium acetate in… read more here.
Keywords: evaluation cytotoxicity; cytotoxicity hela; cyclohexanopregnanes evaluation; synthesis hetero ... See more keywords