BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands.
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DOI: 10.18632/oncotarget.17834
Abstract: Using syngeneic BALB/c mouse breast cancer models, we show that the chromatin remodeling subunit bromodomain PHD finger transcription factor (BPTF) suppresses natural killer (NK) cell antitumor activity in the tumor microenvironment (TME). In culture, BPTF… read more here.
Keywords: bptf; cell activity; natural cytotoxicity; cytotoxicity receptor ... See more keywords