Articles with "cyy 287" as a keyword



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cyy-287, a novel pyrimidine-2,4-diamine derivative, inhibits tumor growth of EGFR-driven non-small cell lung cancer via the ERK pathway

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Published in 2022 at "Acta Biochimica et Biophysica Sinica"

DOI: 10.3724/abbs.2022139

Abstract: In recent decades, EGFR-targeted tyrosine kinase inhibitors (TKIs) have been proven to be an effective therapy for EGFR-mutant non-small cell lung cancer (NSCLC). However, resistance to EGFR-TKIs limits their clinical application. In the present study,… read more here.

Keywords: erk pathway; cyy 287; non small; egfr driven ... See more keywords