Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function.
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DOI: 10.1016/j.bbrc.2018.10.180
Abstract: AIMS Therapies that recapitulate the health benefits of caloric restriction in older adults are needed. Phosphodiesterase 4 inhibitors demonstrate such promise. We examined their effects on body weight and composition, physical and cognitive function in… read more here.
Keywords: mass; d159687; aged mice; mice ... See more keywords