Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modifications
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DOI: 10.1007/s43440-021-00352-x
Abstract: Background Allosteric modulation of G protein-coupled receptors (GPCRs) is nowadays one of the hot topics in drug discovery. In particular, allosteric modulators of D2 receptor have been proposed as potential modern therapeutics to treat schizophrenia… read more here.
Keywords: modulator; d2l receptor; allosteric modulation; receptor ... See more keywords