Articles with "d2rspi" as a keyword



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Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone

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Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-20221-0

Abstract: In addition to the serotonin 5-HT2A receptor (5-HT2AR), the dopamine D2 receptor (D2R) is a key therapeutic target of antipsychotics for the treatment of schizophrenia. The inactive state structures of D2R have been described in… read more here.

Keywords: d2r; d2rspi; dopamine receptor; structure ... See more keywords