3H-1,2-Dithiole-3-thione as a novel therapeutic agent for the treatment of ischemic stroke through Nrf2 defense pathway
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.01.018
Abstract: Cerebral ischemic stroke accounts for more than 80% of all stroke cases. During cerebral ischemia, reactive oxygen species produced in brain tissue induce oxidative stress and inflammatory responses. D3T, the simplest compound of the cyclic,… read more here.
Keywords: ischemic stroke; treatment ischemic; activation; brain ... See more keywords
D3T acts as a pro-oxidant in a cell culture model of diabetes-induced peripheral neuropathy
Sign Up to like & getrecommendations! Published in 2019 at "Redox Biology"
DOI: 10.1016/j.redox.2018.101078
Abstract: Diabetes mellitus is one of the most common chronic diseases in the United States and peripheral neuropathy (PN) affects at least 50% of diabetic patients. Medications available for patients ameliorate symptoms (pain), but do not… read more here.
Keywords: age; peripheral neuropathy; model; damage ... See more keywords