Articles with "d473h" as a keyword



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Molecular modeling study on resistance of WT/D473H SMO to antagonists LDE‐225 and LEQ‐506

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Published in 2018 at "Pharmacological Research"

DOI: 10.1016/j.phrs.2017.11.025

Abstract: Graphical abstract The superposition between apo‐WT (pink) and apo‐D473H (palecyan) (a), the hydrogen bonds network and free energy surface of the wild type residue Asp473 (b and d) and the mutant residue His473 (c and… read more here.

Keywords: lde 225; smo; leq 506; resistance ... See more keywords