A bivalent vaccine containing D614G and BA.1 spike trimer proteins or a BA.1 spike trimer protein booster shows broad neutralizing immunity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27885
Abstract: The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron variant, sublineages BA.1 and BA.2, recently became the dominant variants of concern (VOCs) with significantly higher transmissibility than any other variant appeared and markedly… read more here.
Keywords: vaccine; spike trimer; d614g; protein ... See more keywords
Dynamics prediction of emerging notable spike protein mutations in SARS-CoV-2 implies a need for updated vaccines
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.08.011
Abstract: The spike protein of SARS-CoV-2 plays a crucial role in binding with the human cell surface, which causes its pathogenicity. This study aimed to predict molecular dynamics change of emerging variants in the spike protein.… read more here.
Keywords: protein; spike protein; d614g; sars cov ... See more keywords
Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear
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DOI: 10.1016/j.cell.2020.06.040
Abstract: Abstract Korber et al. (2020) found that a SARS-CoV-2 variant in the spike protein, D614G, rapidly became dominant around the world. While clinical and in vitro data suggest that D614G changes the virus phenotype, the… read more here.
Keywords: d614g means; mutation d614g; d614g; sense mutation ... See more keywords
Estimating the transmission advantage of the D614G mutant strain of SARS-CoV-2, December 2019 to June 2020
Sign Up to like & getrecommendations! Published in 2021 at "Eurosurveillance"
DOI: 10.2807/1560-7917.es.2021.26.49.2002005
Abstract: Introduction The SARS-CoV-2 lineages carrying the amino acid change D614G have become the dominant variants in the global COVID-19 pandemic. By June 2021, all the emerging variants of concern carried the D614G mutation. The rapid… read more here.
Keywords: transmission advantage; advantage d614g; strain; sars cov ... See more keywords
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.65365
Abstract: A novel variant of the SARS-CoV-2 virus carrying a point mutation in the Spike protein (D614G) has recently emerged and rapidly surpassed others in prevalence. This mutation is in linkage disequilibrium with an ORF1b protein… read more here.
Keywords: d614g; d614g mutation; spike d614g; sars cov ... See more keywords