Enterovirus D68-Associated Community-Acquired Pneumonia in the Pediatric Age Group
Sign Up to like & getrecommendations! Published in 2017 at "Current Infectious Disease Reports"
DOI: 10.1007/s11908-017-0567-8
Abstract: Purpose of ReviewThis review summarizes the current knowledge regarding the role of Enterovirus D68 (EV-D68) in community-acquired pneumonia (CAP) in children.Recent FindingsEV-D68 is an emergent viral pathogen. Since its first isolation in 1962 in California… read more here.
Keywords: community; community acquired; enterovirus d68; d68 associated ... See more keywords
Enterovirus D68 antivirals: past, present and future.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00120
Abstract: Enterovirus D68 (EV-D68) is an RNA virus that causes respiratory illnesses mainly in children. In severe cases, it can lead to neurological complications such as acute flaccid myelitis (AFM). EV-D68 belongs to the enterovirus genera… read more here.
Keywords: future; enterovirus d68; d68 antivirals; antivirals past ... See more keywords
Characterization of a new anti-enterovirus 68 compound purified from avocado.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00404
Abstract: One of the major challenges in development of anti-enterovirus (EV) drug is in the safety of the drug. Here, we attempt to identity anti-EV compound from an edible plant extract library, and identify potent anti-enterovirus… read more here.
Keywords: anti enterovirus; new anti; compound; characterization new ... See more keywords
Current Understanding of Humoral Immunity to Enterovirus D68.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piy124
Abstract: Enterovirus D68 (EV-D68) is a pathogen that causes outbreaks of respiratory illness across the world, mostly in children, and can be especially severe in those with asthma. Clusters of acute flaccid myelitis, a poliomyelitis-like neuromuscular… read more here.
Keywords: immunity enterovirus; understanding humoral; humoral immunity; enterovirus d68 ... See more keywords
Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001356
Abstract: EV-D68 is an emerging enterovirus infection associated with severe acute respiratory illness (SARI), acute flaccid myelitis (AFM) and acute flaccid paralysis (AFP). While EV-D68 outbreaks and sporadic cases are reported globally, a single case has… read more here.
Keywords: analysis enterovirus; south india; epidemiology; d68 associated ... See more keywords
Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015
Sign Up to like & getrecommendations! Published in 2019 at "Pediatrics International"
DOI: 10.1111/ped.13903
Abstract: Outbreaks of enterovirus D68 (EV‐D68) respiratory infections in children were reported globally in 2014. In Japan, there was an EV‐D68 outbreak in the autumn of 2015 (September–October). The aim of this study was to compare… read more here.
Keywords: d68 respiratory; respiratory infection; enterovirus d68; japan ... See more keywords
Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00227-22
Abstract: Enterovirus D68 (EV-D68) can cause mild to severe respiratory illness and is associated with a poliomyelitis-like paralytic syndrome called acute flaccid myelitis (AFM). Most cases of EV-D68-associated AFM occur in young children who are brought… read more here.
Keywords: d68; paralysis; onset; flaccid myelitis ... See more keywords
Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01694-22
Abstract: Recent outbreaks of enterovirus D68, a nonpolio enterovirus, is associated with a serious neurological condition in young children, acute flaccid myelitis (AFM). As there is no antiviral treatment or vaccine available for EV-D68 it is… read more here.
Keywords: d68; infection; brain; d68 infection ... See more keywords
Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes
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DOI: 10.1128/spectrum.02452-21
Abstract: Despite the strong causal link between enterovirus D68 (EV-D68) and acute flaccid myelitis (AFM), it remains unclear how EV-D68 gains entry into the central nervous system and what receptors enable it to infect motor neurons.… read more here.
Keywords: density; d68; motor; enterovirus d68 ... See more keywords
Enterovirus D68 VP3 Targets the Interferon Regulatory Factor 7 To Inhibit Type I Interferon Response
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DOI: 10.1128/spectrum.04138-22
Abstract: EV-D68 is a globally emerging pathogen that causes severe respiratory illnesses. Here, we report that EV-D68 inhibits innate immune responses by targeting IRF7. Further investigations revealed that the structural protein VP3 inhibited the TRAF6-induced ubiquitination… read more here.
Keywords: vp3; interaction; d68; structural protein ... See more keywords
Global prevalence and case fatality rate of Enterovirus D68 infections, a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010073
Abstract: A substantial amount of epidemiological data has been reported on Enterovirus D68 (EV-D68) infections after the 2014 outbreak. Our goal was to map the case fatality rate (CFR) and prevalence of current and past EV-D68… read more here.
Keywords: fatality rate; d68; d68 infections; prevalence ... See more keywords