Seroprevalence of enterovirus D68 in Yamagata, Japan, between 1976 and 2019
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.29947
Abstract: To clarify the epidemiology of enterovirus D68 (EV‐D68), an enterovirus rarely identified in the 20th century, we performed seroepidemiological analysis against EV‐D68 using sera collected in 1976, 1985, 1990, 1999, 2009, and 2019, as well… read more here.
Keywords: japan; enterovirus d68; yamagata japan; d68 ... See more keywords
Enterovirus D68: A Novel Inhibitor Reveals Underlying Molecular Mechanisms of Viral Entry and Uncoating
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DOI: 10.1002/jmv.70677
Abstract: While enterovirus D68 (EV‐D68) has emerged as a significant pediatric pathogen causing severe respiratory illness and acute flaccid myelitis, no effective therapeutics exist. Through systematic screening of natural products, we identified geranyl‐p‐trans‐coumaric acid (GCA) as… read more here.
Keywords: viral entry; inhibitor; enterovirus d68; d68 ... See more keywords
Enterovirus D68-Associated Community-Acquired Pneumonia in the Pediatric Age Group
Sign Up to like & getrecommendations! Published in 2017 at "Current Infectious Disease Reports"
DOI: 10.1007/s11908-017-0567-8
Abstract: Purpose of ReviewThis review summarizes the current knowledge regarding the role of Enterovirus D68 (EV-D68) in community-acquired pneumonia (CAP) in children.Recent FindingsEV-D68 is an emergent viral pathogen. Since its first isolation in 1962 in California… read more here.
Keywords: community; community acquired; enterovirus d68; d68 associated ... See more keywords
Enterovirus D68 antivirals: past, present and future.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00120
Abstract: Enterovirus D68 (EV-D68) is an RNA virus that causes respiratory illnesses mainly in children. In severe cases, it can lead to neurological complications such as acute flaccid myelitis (AFM). EV-D68 belongs to the enterovirus genera… read more here.
Keywords: future; enterovirus d68; d68 antivirals; antivirals past ... See more keywords
Characterization of a new anti-enterovirus 68 compound purified from avocado.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00404
Abstract: One of the major challenges in development of anti-enterovirus (EV) drug is in the safety of the drug. Here, we attempt to identity anti-EV compound from an edible plant extract library, and identify potent anti-enterovirus… read more here.
Keywords: anti enterovirus; new anti; compound; characterization new ... See more keywords
Detection of Enteroviruses in a Pediatric Oncology Patient Population
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqae129.365
Abstract: Enteroviruses are responsible for around 10 to 15 million infections and tens of thousands of hospitalizations annually. Infants, children, and people with weakened immune systems are more likely to get hospitalized and can have serious… read more here.
Keywords: oncology; oncology patient; pediatric oncology; d68 ... See more keywords
Current Understanding of Humoral Immunity to Enterovirus D68.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piy124
Abstract: Enterovirus D68 (EV-D68) is a pathogen that causes outbreaks of respiratory illness across the world, mostly in children, and can be especially severe in those with asthma. Clusters of acute flaccid myelitis, a poliomyelitis-like neuromuscular… read more here.
Keywords: immunity enterovirus; understanding humoral; humoral immunity; enterovirus d68 ... See more keywords
Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001356
Abstract: EV-D68 is an emerging enterovirus infection associated with severe acute respiratory illness (SARI), acute flaccid myelitis (AFM) and acute flaccid paralysis (AFP). While EV-D68 outbreaks and sporadic cases are reported globally, a single case has… read more here.
Keywords: analysis enterovirus; south india; epidemiology; d68 associated ... See more keywords
Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015
Sign Up to like & getrecommendations! Published in 2019 at "Pediatrics International"
DOI: 10.1111/ped.13903
Abstract: Outbreaks of enterovirus D68 (EV‐D68) respiratory infections in children were reported globally in 2014. In Japan, there was an EV‐D68 outbreak in the autumn of 2015 (September–October). The aim of this study was to compare… read more here.
Keywords: d68 respiratory; respiratory infection; enterovirus d68; japan ... See more keywords
Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00227-22
Abstract: Enterovirus D68 (EV-D68) can cause mild to severe respiratory illness and is associated with a poliomyelitis-like paralytic syndrome called acute flaccid myelitis (AFM). Most cases of EV-D68-associated AFM occur in young children who are brought… read more here.
Keywords: d68; paralysis; onset; flaccid myelitis ... See more keywords
Pharmacological activation of TLR7 exerts inhibition on the replication of EV-D68 in respiratory cells
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Virology"
DOI: 10.1128/jvi.00434-24
Abstract: ABSTRACT The globally reemerging respiratory pathogen enterovirus D68 (EV-D68) is implicated in outbreaks of severe respiratory illness and associated with acute flaccid myelitis. However, there remains a lack of effective treatments for EV-D68 infection. In… read more here.
Keywords: replication; respiratory; d68; tlr7 ... See more keywords