SNAP23 is essential for germination of EV-D68 replication organelles.
Sign Up to like & getrecommendations! Published in 2022 at "Virology"
DOI: 10.2139/ssrn.4226394
Abstract: Picornaviruses rearrange host cell membranes to facilitate their own replication. Here we investigate the Qbc SNARE, SNAP23, which is found at the plasma membrane and plays roles in exocytosis. We found that knockdown of SNAP23… read more here.
Keywords: replication organelles; replication; snap23 essential; rna replication ... See more keywords
Andrographolide Prevents EV-D68 Replication by Inhibiting the Acidification of Virus-Containing Endocytic Vesicles
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.02407
Abstract: Enterovirus D68 (EV-D68) has emerged as a significant respiratory pathogen that can cause severe respiratory disease and acute neurologic disease. At present, there are no approved antiviral agents or vaccines for EV-D68. In this study,… read more here.
Keywords: d68; acidification; endocytic vesicles; virus containing ... See more keywords