Reduction in liver transplant wait‐listing in the era of direct‐acting antiviral therapy
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DOI: 10.1002/hep.28923
Abstract: Direct‐acting antiviral (DAA) therapy, recently approved for patients with decompensated cirrhosis (DC) secondary to hepatitis C virus (HCV), is associated with improved hepatic function. We analyzed trends in liver transplant (LT) wait‐listing (WL) to explore… read more here.
Keywords: era; daa; direct acting; acting antiviral ... See more keywords
Evaluation of hepatitis B reactivation among 62,920 veterans treated with oral hepatitis C antivirals
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DOI: 10.1002/hep.29135
Abstract: Reactivation of hepatitis B virus (HBV) has been reported in hepatitis C virus–infected individuals receiving direct‐acting antiviral (DAA) therapy. The overall risk among patients with current or prior HBV infection in the context of DAA… read more here.
Keywords: hepatitis; daa; hbv reactivation; reactivation ... See more keywords
Autoantibodies against “rods and rings”-related IMPDH2 in hepatitis C genotype 1 and DAA therapy in a “real life” cohort
Sign Up to like & getrecommendations! Published in 2017 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-017-0516-z
Abstract: Autoantibodies against inosine-5′-monophosphate-dehydrogenase-2 (IMPDH2; “rods and rings” pattern) develop in chronic hepatitis C (CHC) patients under treatment with peg-interferon (IFN) and ribavirin (RBV), an inhibitor of IMPDH2. We investigated the influence of the alternative therapy… read more here.
Keywords: daa; rods rings; anti impdh2; therapy ... See more keywords
The cyclization mechanism of cis DAA-DAA dipeptide: an ab initio study
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DOI: 10.1007/s11224-018-1085-5
Abstract: The gas-phase cyclization mechanism of cis DAA-DAA dipeptide (where DAA stands for the earlier described double amino acid molecule of (NH2)2C(COOH)2 formula while DAA-DAA indicates the system formed by two DAAs linked via the peptide… read more here.
Keywords: daa daa; mechanism; daa; cyclization ... See more keywords
Effect of wheat infection timing on Fusarium head blight causal agents and secondary metabolites in grain.
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DOI: 10.1016/j.ijfoodmicro.2018.10.014
Abstract: Fusarium head blight (FHB) results in yield loss and damaging contamination of cereal grains and can be caused by several Fusarium species. The objective of the present study was to determine, in a greenhouse experiment… read more here.
Keywords: daa daa; fusarium head; infection; daa ... See more keywords
Three cases of incident lichen planus after direct-acting antiviral treatment for hepatitis C
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DOI: 10.1016/j.jdcr.2018.10.004
Abstract: DAA: direct-acting antiviral HCV: hepatitis C virus LP: lichen planus SVR: sustained viral response UCSF: University of California, San Francisco H epatitis C virus (HCV) infection is associated with many extrahepatic manifestations, including skin diseases… read more here.
Keywords: treatment; daa; hcv; direct acting ... See more keywords
Efficacy and safety of direct-acting antiviral regimens in HIV/HCV-co-infected patients - French ANRS CO13 HEPAVIH cohort.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2017.02.012
Abstract: BACKGROUND & AIMS There is little data available on the use of new oral direct-acting antiviral (DAA) regimens to treat human immunodeficiency virus and hepatitis C virus (HIV/HCV) co-infected patients in real-life settings. Here, the… read more here.
Keywords: hcv infected; daa; cohort; hiv hcv ... See more keywords
HCV eradication induced by direct-acting antiviral agents reduces the risk of hepatocellular carcinoma.
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DOI: 10.1016/j.jhep.2017.08.030
Abstract: BACKGROUND & AIMS It is unclear whether direct-acting antiviral (DAA) treatment-induced sustained virologic response (SVR) reduces the risk of hepatocellular carcinoma (HCC) in patients with HCV infection. Therefore, in the current study, our aim was… read more here.
Keywords: risk; hcc; treatment; ifn ... See more keywords
Impact of DAAs on liver transplantation: Major effects on the evolution of indications and results. An ELITA study based on the ELTR registry.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2018.06.010
Abstract: BACKGROUND & AIMS Direct-acting antivirals (DAAs) have dramatically improved the outcome of patients with hepatitis C virus (HCV) infection including those with decompensated cirrhosis (DC). We analyzed the evolution of indications and results of liver… read more here.
Keywords: hcv; daa; study; liver ... See more keywords
Metabolic Labeling Strategy Boosted Antibacterial Efficiency for Photothermal and Photodynamic Synergistic Bacteria-Infected Wound Therapy.
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DOI: 10.1021/acsami.2c15759
Abstract: Pathogenic bacteria infections bring about a substantial risk to human health. Given the development of antibiotic-resistance bacteria, alternative antibacterial strategies with great inactivation efficiency and bacteria-binding ability are extremely attractive. In this work, a metabolic… read more here.
Keywords: photothermal photodynamic; antibacterial efficiency; daa; metabolic labeling ... See more keywords
Characterization of multi-DAA resistance using a novel hepatitis C virus genotype 3a infectious culture system.
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DOI: 10.1097/hep.0000000000000353
Abstract: BACKGROUND AIMS The high hepatitis C virus (HCV) infection cure rates achieved with direct-acting antiviral (DAA) treatments could be compromised in the future by the emergence of antiviral resistance. Thus, it is essential to understand… read more here.
Keywords: daa resistance; daa; resistance; treatment failure ... See more keywords