The effects of direct‐acting antiviral agents on the frequency of myeloid‐derived suppressor cells and natural killer cells in patients with chronic hepatitis C
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25302
Abstract: Currently, hepatitis C antiviral therapy is entering a new era with the use of direct‐acting antiviral (DAA) agents. However, the precise immunological influences of DAA therapy in patients with chronic hepatitis C (CHC) are insufficiently… read more here.
Keywords: hepatitis; frequency; direct acting; acting antiviral ... See more keywords
Direct‐acting antivirals and recurrence of hepatocellular carcinoma
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DOI: 10.1002/lt.24822
Abstract: Given the high prevalence of hepatitis C virus (HCV) in an aging population, it is estimated that HCVrelated hepatocellular carcinoma (HCC) will continue to be a major source of morbidity and mortality until at least… read more here.
Keywords: hcc; recurrence; group; therapy ... See more keywords
Direct-Acting Antivirals Decreased Tumor Recurrence After Initial Treatment of Hepatitis C Virus-Related Hepatocellular Carcinoma
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DOI: 10.1007/s10620-017-4739-z
Abstract: BackgroundSuppressive activity of recurrence by interferon-free direct-acting antivirals (DAA) is not elucidated after curative treatment of hepatocellular carcinoma (HCC).Patients and MethodsA total of 177 patients received DAA after curative manners of HCC: 89 patients underwent… read more here.
Keywords: recurrence; hcc therapy; therapy; initial hcc ... See more keywords
Is there increased risk of hepatocellular carcinoma recurrence in liver transplant patients with direct-acting antiviral therapy?
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology International"
DOI: 10.1007/s12072-019-09930-x
Abstract: BackgroundRecently, a controversy has emerged: is the rate of recurrence of hepatocellular carcinoma (HCC) higher following treatment of hepatitis C virus (HCV) with direct-acting antiviral (DAA) therapy? However, the risk of HCC recurrence has not… read more here.
Keywords: recurrence; group; hcc recurrence; therapy ... See more keywords
Immunological recovery in T-cell activation after sustained virologic response among HIV positive and HIV negative chronic Hepatitis C patients
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DOI: 10.1007/s12072-019-09941-8
Abstract: BackgroundRapid decreases in activated CD4+ and CD8+ (HLA-DR + and CD38+ co-expressed) T-lymphocytes have been described within 1–2 weeks of initiating direct-acting antiviral (DAA) therapy among chronic Hepatitis C (CHC) patients. However, it is not known whether these changes are maintained… read more here.
Keywords: hiv hcv; hcv; hcv coinfected; daa therapy ... See more keywords
Direct-Acting Antiviral Therapy for HCV Infection is Associated with Increased Survival in Patients With a History of Hepatocellular Carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2019.07.040
Abstract: BACKGROUND & AIMS There is controversy over benefits of direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection for patients with a history of hepatocellular carcinoma (HCC). We performed a multicenter cohort study to… read more here.
Keywords: response; hcv infection; direct acting; therapy ... See more keywords
Transient elastography score is elevated during rheumatoid factor-positive chronic hepatitis C virus infection and rheumatoid factor decline is highly variable over the course of direct-acting antiviral therapy
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DOI: 10.1371/journal.pone.0267512
Abstract: Background Elevated rheumatoid factor (RF) levels and systemic immune activation are highly prevalent during chronic hepatitis C virus (HCV) infection. Direct-acting antiviral (DAA) therapy has been associated with normalization of various soluble immune activation parameters.… read more here.
Keywords: infection; rheumatoid factor; therapy; hcv ... See more keywords
Role of LI-RADS Indeterminate Observations in the Risk of Hepatocellular Carcinoma after HCV Eradication with Direct-Acting Antivirals
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DOI: 10.3390/diagnostics12051187
Abstract: Purpose: To assess whether HCC (LR-5) occurrence may be associated with the presence of Liver Imaging Reporting and Data System (LI-RADS) indeterminate observations in patients with hepatitis C virus infection treated with direct acting antiviral… read more here.
Keywords: role rads; rads indeterminate; indeterminate observations; eradication ... See more keywords
Effect of Direct-Acting Antiviral Agents on Gastroesophageal Varices in Patients with Hepatitis C Virus-Related Cirrhosis
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DOI: 10.3390/medicina58081077
Abstract: Aim: In patients with hepatitis C virus-related liver cirrhosis (LC) who achieve sustained virological responses (SVRs) through treatment with direct-acting antiviral agents (DAAs), it remains unclear whether there are improvements in gastroesophageal varices (GEVs) and… read more here.
Keywords: virus related; patients hepatitis; gevs; therapy ... See more keywords