Insights in to the mechanism of interaction of a thrombin inhibitor, dabigatran etexilate with human serum albumin and influence of β-cyclodextrin on binding: Spectroscopic and computational approach
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DOI: 10.1016/j.molliq.2017.12.056
Abstract: Abstract The present work investigates the characteristics of interaction of a thrombin inhibitor, dabigatran etexilate (DAB) with a model transport protein, human serum albumin (HSA). In vitro studies on DAB-HSA interactions were carried out by… read more here.
Keywords: thrombin inhibitor; inhibitor dabigatran; human serum; dabigatran etexilate ... See more keywords
Anticoagulation efficacy of dabigatran etexilate for left atrial appendage thrombus in patients with atrial fibrillation by transthoracic and transesophageal echocardiography
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000011117
Abstract: Abstract To evaluate the anticoagulation efficacy of dabigatran etexilate for left atrial appendage (LAA) thrombus resolution in patients with atrial fibrillation by transthoracic echocardiography and transesophageal echocardiography, and to investigate the anticoagulation factors. A total… read more here.
Keywords: atrial fibrillation; anticoagulation; group; dabigatran etexilate ... See more keywords
Effects of Simvastatin on Pharmacokinetics and Anticoagulant Effects of Dabigatran in Healthy Subjects
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DOI: 10.3390/ph16030364
Abstract: Higher risk of major hemorrhage associated with concomitant use of dabigatran and simvastatin compared to other statins was previously reported with a suggestion of P-glycoprotein-mediated interaction. The aim of this study was to evaluate the… read more here.
Keywords: pharmacokinetics anticoagulant; dabigatran; effects dabigatran; anticoagulant effects ... See more keywords
Activated charcoal can be used to aid the diagnosis of an overdose of dabigatran etexilate.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of clinical pharmacology and therapeutics"
DOI: 10.5414/cp204225
Abstract: The direct-acting oral anticoagulant dabigatran etexilate (DE prevent systemic thromboembolism and cerebral apoplexy in patients with nonvalvular atrial fibrillation. On September 22, 2021, an 86-year-old female patient in Peking University People's Hospital presented with a… read more here.
Keywords: dabigatran etexilate; coagulation; activated charcoal;