Dabigatran - Metabolism, Pharmacologic Properties and Drug Interactions.
Sign Up to like & getrecommendations! Published in 2017 at "Current drug metabolism"
DOI: 10.2174/1389200218666170427113504
Abstract: BACKGROUND The superiority of dabigatran has been well proven in the standard dosing regimen in prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF) and extended venous thromboembolism (VTE) treatment. Dabigatran,… read more here.
Keywords: drug; renal function; dabigatran; dabigatran metabolism ... See more keywords
SLC4A4, FRAS1, and SULT1A1 Genetic Variations Associated With Dabigatran Metabolism in a Healthy Chinese Population
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.873031
Abstract: Background: The purpose of this study was to identify genetic variations associated with the metabolism of dabigatran in healthy Chinese subjects, with particular focus given to pharmacokinetics (PK) and pharmacodynamics (PD). Methods: Healthy Chinese adults… read more here.
Keywords: metabolism; variations associated; genetic variations; dabigatran metabolism ... See more keywords