Nodal induced by hypoxia exposure contributes to dacarbazine resistance and the maintenance of stemness in melanoma cancer stem‑like cells.
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DOI: 10.3892/or.2018.6387
Abstract: Nodal signaling has a critical role in the processes of embryogenesis and is necessary for maintaining cell stemness. However, its upregulation in melanoma is positively correlated with malignant potential, including cancer progression, metastasis and recurrence,… read more here.
Keywords: melanoma; dacarbazine resistance; hypoxia exposure; cancer ... See more keywords