High-fat diet-induced hypertension is associated with a proinflammatory T cell profile in male and female Dahl salt-sensitive rats
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Physiology - Heart and Circulatory Physiology"
DOI: 10.1152/ajpheart.00389.2018
Abstract: Evidence supports a sex difference in the impact of a high-fat diet (HFD) on cardiovascular outcomes, with male experimental animals exhibiting greater increases in blood pressure (BP) than female experimental animals. The immune system has… read more here.
Keywords: fat diet; hfd; male female; high fat ... See more keywords
Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome.
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hypertensionaha.119.12927
Abstract: The Dahl salt-sensitive (SS) rat is an established model of SS hypertension and renal damage. In addition to salt, other dietary components were shown to be important determinants of hypertension in SS rats. With previous… read more here.
Keywords: dahl salt; renal damage; hypertension renal; salt ... See more keywords
FPR-1 (Formyl Peptide Receptor-1) Activation Promotes Spontaneous, Premature Hypertension in Dahl Salt-Sensitive Rats
Sign Up to like & getrecommendations! Published in 2021 at "Hypertension"
DOI: 10.1161/hypertensionaha.120.16237
Abstract: Supplemental Digital Content is available in the text. Cell death has long been a characteristic phenotype of organ damage in hypertension, and recently, leaky gut has been revealed as a novel hypertensive phenotype. However, despite… read more here.
Keywords: dahl salt; salt sensitive; salt; hypertension ... See more keywords
Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.543727
Abstract: Regulation of the peripheral vascular resistance via modulating the vessel diameter has been considered as a main determinant of the arterial blood pressure. Phosphodiesterase enzymes (PDE1-11) hydrolyse cyclic nucleotides, which are key players controlling the… read more here.
Keywords: sensitive rats; blood pressure; salt sensitive; blood ... See more keywords
Association of Antihypertensive Effects of Esaxerenone with the Internal Sodium Balance in Dahl Salt-Sensitive Hypertensive Rats
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DOI: 10.3390/ijms23168915
Abstract: Background: The nonsteroidal mineralocorticoid receptor blocker esaxerenone is effective in reducing blood pressure (BP). Objective: In this study, we investigated esaxerenone-driven sodium homeostasis and its association with changes in BP in Dahl salt-sensitive (DSS) hypertensive… read more here.
Keywords: sodium; salt sensitive; dahl salt; treated rats ... See more keywords
Dahl Salt-Resistant Rat Is Protected against Hypertension during Diet-Induced Obesity
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14183843
Abstract: A high-fat diet (HFD) frequently causes obesity-induced hypertension. Because Dahl salt-resistant rats are protected against hypertension after high-salt or high-fructose intake, it is of interest whether this model also protects against hypertension after diet-induced obesity.… read more here.
Keywords: salt resistant; hypertension; hypertension diet; obesity ... See more keywords