Daisy Chain Topology based mammalian synthetic circuits for RNA-only delivery.
Sign Up to like & getrecommendations! Published in 2020 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.9b00313
Abstract: Owing to the superiority in safety, RNA-only delivery synthetic circuit is more suitable for cell-based medicine. Modules which possess matching inputs and outputs could be stringed by daisy-chaining to compose RNA-only delivery synthetic gene circuits.… read more here.
Keywords: synthetic circuits; topology; rna delivery; daisy chain ... See more keywords
Daisy Chain Dendrimers: Integrated Mechanically Interlocked Molecules with Stimuli-induced Dimension Modulation Feature.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c02475
Abstract: The precise construction of the high-order mechanically interlocked molecules (MIMs) with well-defined topological arrangements of multiple mechanically interlocked units has been a great challenge. Herein, we present the first successful preparation of a new family… read more here.
Keywords: chain; mechanically interlocked; interlocked molecules; chain dendrimers ... See more keywords
Light-controlled interconversion between a [c2]daisy chain and a lasso-type pseudo[1]rotaxane.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc04419b
Abstract: A light-responsive self-complementary crown ether/ammonium conjugate bearing an arylazopyrazole photoswitch as a spacer can be switched between a [c2]daisy chain (E-isomer) and a lasso-type pseudo[1]rotaxane (Z-isomer) by light. read more here.
Keywords: pseudo rotaxane; lasso type; daisy chain; type pseudo ... See more keywords
Daisy-chain gene drives for the alteration of local populations
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1716358116
Abstract: Significance CRISPR-based gene drive systems—genetic elements which could be engineered to rapidly spread traits through wild populations—could help solve some of humanity’s greatest ecological and public health problems. However, if released, current versions might spread… read more here.
Keywords: gene; drive; daisy chain; crispr based ... See more keywords