A Dalbavancin Lock Solution Can Reduce Enterococcal Biofilms After Freezing
Sign Up to like & getrecommendations! Published in 2022 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-021-00579-4
Abstract: We previously demonstrated the efficacy of a frozen dalbavancin–heparin (DH) lock solution against biofilms of staphylococci. However, as enterococci also commonly cause catheter-related bloodstream infections (C-RBSI), we assessed the bioactivity of frozen dalbavancin (D) and… read more here.
Keywords: lock solution; solution; dalbavancin lock; enterococcal biofilms ... See more keywords
Budget Impact Analysis of Dalbavancin in the Treatment of Acute Bacterial Skin and Skin Structure Infections in Three European Countries
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Drug Investigation"
DOI: 10.1007/s40261-020-00891-w
Abstract: Background and Objective Acute bacterial skin and skin structure infections (ABSSSIs) have been defined by the US Food and Drug Administration (FDA) in 2013 to include a subset of complicated skin and skin structure infections… read more here.
Keywords: skin skin; analysis; skin; structure infections ... See more keywords
Comparison of dalbavancin to standard-of-care for outpatient treatment of invasive Gram-positive infections.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2020.106210
Abstract: OBJECTIVE To assess the efficacy and safety of dalbavancin compared to standard-of-care (SOC) or vancomycin and daptomycin in invasive infections due to suspected or confirmed Gram-positive organisms. METHODS Retrospective cohort of adults who received dalbavancin or… read more here.
Keywords: standard care; gram positive; dalbavancin; soc ... See more keywords
Dalbavancin for treatment of implant-related methicillin-resistant Staphylococcus aureus osteomyelitis in an experimental rat model
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28006-8
Abstract: Dalbavancin is a new semisynthetic lipoglycopeptide with improved antimicrobial activity against various gram-positive pathogens. It demonstrates an extensive plasma half-life which permits outpatient parenteral antimicrobial therapy with weekly intervals and might therefore be an excellent… read more here.
Keywords: implant related; aureus; treatment; dalbavancin ... See more keywords
Dalbavancin treatment for spondylodiscitis: multi-center clinical experience and literature review.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chemotherapy"
DOI: 10.1080/1120009x.2021.2015649
Abstract: Dalbavancin is a novel lipoglycopeptide antibiotic, characterized by a broad spectrum of activity against Gram-positive cocci. However, its efficacy in spondylodiscitis treatment is not fully established. All adult patients diagnosed with spondylodiscitis and treated with… read more here.
Keywords: dalbavancin; treatment; literature review; spondylodiscitis ... See more keywords
A cost-minimization analysis of dalbavancin compared to conventional therapy for the outpatient treatment of acute bacterial skin and skin-structure infections
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2018.1442439
Abstract: ABSTRACT Introduction: Acute bacterial skin and skin-structure infections (ABSSSI) are common infectious diseases (ID) that often require intravenous (IV) antibiotics. Dalbavancin is a novel lipoglycopeptide antibiotic administered once that is FDA-approved for the treatment of… read more here.
Keywords: treatment; skin; conventional therapy; dalbavancin ... See more keywords
Direct or early discharge of Acute Bacterial Skin and Skin Structure Infection patients from the Emergency Department/Unit: Place of therapy of Dalbavancin.
Sign Up to like & getrecommendations! Published in 2023 at "Expert review of anti-infective therapy"
DOI: 10.1080/14787210.2023.2214727
Abstract: INTRODUCTION Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) are a common reason of Emergency Department (ED) access and account for a considerable number of hospital admissions and a high economic burden for the healthcare… read more here.
Keywords: skin; dalbavancin; therapy; early discharge ... See more keywords
Emerging resistance in Staphylococcus epidermidis during dalbavancin exposure: a case report and in vitro analysis of isolates from prosthetic joint infections
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac434
Abstract: Abstract Background Dalbavancin, a semisynthetic lipoglycopeptide with exceptionally long half-life and Gram-positive spectrum, is an attractive option for infections requiring prolonged therapy, including prosthetic joint infections (PJIs). Objectives To investigate the prevalence of reduced susceptibility… read more here.
Keywords: prosthetic joint; dalbavancin; reduced susceptibility; resistance ... See more keywords
Evaluation of dalbavancin alone and in combination with &bgr;-lactam antibiotics against resistant phenotypes of Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dky376
Abstract: Background Emergence of reduced susceptibility to vancomycin warrants the development of new antimicrobial agents for the treatment of MRSA. We evaluated the activity of dalbavancin, a novel lipoglycopeptide antibiotic, both alone and combined with β-lactams,… read more here.
Keywords: combination; phenotypes staphylococcus; resistant phenotypes; dalbavancin ... See more keywords
122. Dalbavancin Use in Patients with Substance Use Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.432
Abstract: Dalbavancin, a lipoglycopeptide antibiotic, has an extended half-life that allows for weekly dosing and is an alternative to daily intravenous (IV) antibiotics. The dosing interval has the potential to expand treatment options for more severe… read more here.
Keywords: dalbavancin use; use; substance use; patients substance ... See more keywords
Left Ventricular Assist Device Infections and the Potential Role for Dalbavancin: A Case Report
Sign Up to like & getrecommendations! Published in 2019 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofz235
Abstract: Abstract Left ventricular assist device infections (LVADIs) are common but challenging to treat, often requiring prolonged courses of intravenous antibiotics. Dalbavancin could have a role in treating patients with chronic LVADIs given its less frequent… read more here.
Keywords: device infections; assist device; ventricular assist; dalbavancin ... See more keywords