Regulation of endoplasmic reticulum stress on the damage and apoptosis of renal tubular epithelial cells induced by calcium oxalate crystals
Sign Up to like & getrecommendations! Published in 2021 at "Urolithiasis"
DOI: 10.1007/s00240-021-01261-7
Abstract: This study aimed to observe whether calcium oxalate (CaOx) crystals can induce the activation of endoplasmic reticulum (ER) stress in human renal cortex proximal tubule epithelial (HK-2) cells and to explore the regulatory of ER… read more here.
Keywords: cells induced; apoptosis; caox crystals; stress ... See more keywords
The active ingredient (DSH-20) of Salvia miltiorrhiza flower reduces oxidative damage and apoptosis in cardiomyocytes by regulating miR-1.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07207-5
Abstract: BACKGROUND DSH-20, the active ingredient of Salvia miltiorrhiza flower extract, is used to treat cardiovascular diseases. However, its mechanism of action remains unclear. Herein, we investigated the intervention of DSH-20 in H2O2-induced oxidative damage and… read more here.
Keywords: active ingredient; apoptosis; dsh; oxidative damage ... See more keywords
Copper-redox cycling by coumarin-di(2-picolyl)amine hybrid molecule leads to ROS-mediated DNA damage and apoptosis: A mechanism for cancer chemoprevention.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.05.010
Abstract: Coumarin is an important bioactive pharmacophore. It is found in plants as a secondary metabolite and exhibits diverse pharmacological properties including anticancer effects against different malignancies. Therapeutic efficacy of coumarin derivatives depends on the pattern… read more here.
Keywords: cancer; dna damage; damage apoptosis; copper ... See more keywords
Protective effect of diphlorethohydroxycarmalol against oxidative stress-induced DNA damage and apoptosis in retinal pigment epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Cutaneous and Ocular Toxicology"
DOI: 10.1080/15569527.2019.1613425
Abstract: Abstract Purpose: Reactive oxygen species (ROS) contribute to the onset and progression of disease pathogenesis in a variety of organs, including age-related macular degeneration (AMD). Diphlorethohydroxycarmalol (DPHC), a phlorotannin compound, is one of the major… read more here.
Keywords: dna damage; apoptosis; h2o2 induced; damage apoptosis ... See more keywords
Honokiol ameliorates oxidative stress-induced DNA damage and apoptosis of c2c12 myoblasts by ROS generation and mitochondrial pathway
Sign Up to like & getrecommendations! Published in 2020 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2019.1706634
Abstract: ABSTRACT Honokiol is one of the main active components of Magnolia officinalis, and has been demonstrated to have multiple pharmacological activities against a variety of diseases. Recently, this phenolic compound is known to have antioxidant… read more here.
Keywords: induced dna; dna damage; damage apoptosis; c2c12 myoblasts ... See more keywords
Induction of Thioredoxin-Interacting Protein by a Histone Deacetylase Inhibitor, Entinostat, Is Associated with DNA Damage and Apoptosis in Esophageal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-17-1240
Abstract: In 2017, an estimated 17,000 individuals were diagnosed with esophageal adenocarcinoma (EAC), and less than 20% will survive 5 years. Positron emission tomography avidity is indicative of high glucose utilization and is nearly universal in… read more here.
Keywords: dna damage; apoptosis; esophageal adenocarcinoma; damage apoptosis ... See more keywords