To control or to be controlled? Dual roles of CDK2 in DNA damage and DNA damage response.
Sign Up to like & getrecommendations! Published in 2019 at "DNA repair"
DOI: 10.1016/j.dnarep.2019.102702
Abstract: CDK2 (cyclin-dependent kinase 2), a member of the CDK family, has been shown to play a role in many cellular activities including cell cycle progression, apoptosis and senescence. Recently, accumulating evidence indicates that CDK2 is… read more here.
Keywords: dna damage; damage dna; damage; dual roles ... See more keywords
Monte Carlo track-structure for the radionuclide Copper-64: characterization of S-values, nanodosimetry and quantification of direct damage to DNA.
Sign Up to like & getrecommendations! Published in 2020 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/ab8aaa
Abstract: TOPAS-nBio was used to simulate, collision-to-collision, the complete trajectories of electrons in water generated during the explicit simulation of 64Cu decay. S-values and direct damage to the DNA were calculated representing the cell (C) and… read more here.
Keywords: damage dna; cell; configurations respectively; dna ... See more keywords
Synthesis, Radical-Scavenging Activities, and Protective Effects against AAPH-Induced Oxidative Damage in DNA and Erythrocytes of Piperine Derivatives
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DOI: 10.1155/2020/9026286
Abstract: Piperine amino acid derivatives containing phenolic hydroxyl groups were synthesized using piperine as the raw material by amide hydrolysis, amidation, ester hydrolysis, and deacetalization. The obtained products were characterized by mass spectrometry and nuclear magnetic… read more here.
Keywords: damage dna; dna erythrocytes; piperine derivatives; oxidative damage ... See more keywords
The Cellular Response to DNA Damage: From DNA Repair to Polyploidy and Beyond
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076852
Abstract: A major challenge in treating patients with solid tumors is posed by intratumor heterogeneity, with different sub-populations of cancer cells within the same tumor exhibiting therapy resistance through different biological processes [...]. read more here.
Keywords: dna repair; dna; response dna; cellular response ... See more keywords