Telomeres: beacons of autocrine and paracrine DNA damage during skin aging
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DOI: 10.1080/15384101.2020.1728016
Abstract: ABSTRACT Cellular senescence is an irreversible cell cycle arrest, which can be triggered by a number of stressors, including telomere damage. Among many other phenotypic changes, senescence is accompanied by increased secretion of pro-inflammatory molecules,… read more here.
Keywords: senescence; skin aging; damage; damage skin ... See more keywords
UV-induced DNA Damage in Skin is Reduced by CaSR Inhibition.
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DOI: 10.1111/php.13615
Abstract: The epidermis maintains a cellular calcium gradient, that supports keratinocyte differentiation from its basal layers (low) to outer layers (high) leading to the development of the stratum corneum, which resists penetration of UV radiation. The… read more here.
Keywords: damage; damage skin; nps 2143; induced dna ... See more keywords