The percutaneous toxicokinetics of VX in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant
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DOI: 10.1002/jat.3542
Abstract: This study used a damaged skin, porcine model to evaluate the in vivo efficacy of WoundStat™ for the decontamination of superficial, nerve agent‐contaminated wounds. Anaesthetized animals were randomly assigned to either control (n = 7),… read more here.
Keywords: damaged skin; porcine model; decontamination; skin porcine ... See more keywords
A quantitative comparison between SOX10 and MART‐1 immunostaining to detect melanocytic hyperplasia in chronically sun‐damaged skin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.13115
Abstract: Histologic differentiation of melanoma in situ (MIS) from solar keratosis on chronically sun‐damaged skin is challenging. The first‐line immunostain is usually MART‐1/Melan‐A, which can exaggerate the epidermal melanocytes, causing a diagnostic pitfall for MIS. By… read more here.
Keywords: sun damaged; damaged skin; epidermal melanocytes; chronically sun ... See more keywords
Standardization of an in vitro Model for Evaluating the Bioavailability of Topically Applied Compounds on Damaged Skin: Application to Sunscreen Analysis
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DOI: 10.1159/000455196
Abstract: Background: Information is lacking on the dermal penetration of topically applied formulations on in vitro skin models, under conditions where the stratum corneum (SC) is damaged. Therefore, we have developed a standardized in vitro barrier-disrupted… read more here.
Keywords: standardization vitro; topically applied; bioavailability; tape stripping ... See more keywords