Azithromycin enhances the cytotoxicity of DNA‐damaging drugs via lysosomal membrane permeabilization in lung cancer cells
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DOI: 10.1111/cas.14992
Abstract: Cancer cells use autophagy for growth, survival, and cytoprotection from chemotherapy. Therefore, autophagy inhibitors appear to be good candidates for cancer treatment. Our group previously reported that macrolide antibiotics, especially azithromycin (AZM), have potent autophagy… read more here.
Keywords: damaging drugs; dna damaging; treatment; lysosomal membrane ... See more keywords