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Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.102961
Abstract: 20(R)-25-methoxyl-dammarane-3β,12β,20-triol (AD-1, CN Patent: 201010107476.7) is a novel derivative of dammarane-type ginsenoside. AD-1 has been shown to inhibit cancer cell proliferation without significant host toxicity in vivo, and has excellent development potential as a new…
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Keywords:
dammarane;
metabolism;
dammarane type;
cancer ... See more keywords
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Published in 2021 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2020.1851216
Abstract: Abstract Parkinson's disease (PD) is a neurodegenerative disorder that affects adult people whose treatment is palliative. Thus, we decided to test three dammarane triterpenes 1, 1a, 1b, and we determined that 1 and 1a inhibit…
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Keywords:
dammarane;
biological activity;
dammarane triterpenes;
triterpenes targeting ... See more keywords
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Published in 2019 at "Molecules"
DOI: 10.3390/molecules25010139
Abstract: Inflammation is a very common and important pathological process that can cause many diseases. The discovery of anti-inflammatory drugs and the treatment of inflammation are particularly essential. Dammarane-type triterpenoid saponins (PNS) were demonstrated to show…
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Keywords:
dammarane;
triterpenoid saponins;
inhibitory activities;
dammarane type ... See more keywords