Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00741-x
Abstract: It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart disease. Here, in an adaptive, 31-center,… read more here.
Keywords: drug; therapeutic module; danhong injection; day ... See more keywords
Danhong injection represses diabetic retinopathy and nephropathy advancement in diabetic mice by upregulating microRNA-30d-5p and targeting JAK1
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2006964
Abstract: ABSTRACT Danhong injection (DHI) restrains diabetic retinopathy and nephropathy (DR and DN) advancement in diabetic mice. However, the downstream mechanism of its modulation is not fully studied. Diabetic model mice (db/db mice) were intravenously injected… read more here.
Keywords: danhong injection; jak1; mir 30d; mice ... See more keywords
A comparative study of Danhong injection and Salvia miltiorrhiza injection in the treatment of cerebral infarction
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DOI: 10.1097/md.0000000000007079
Abstract: Background: To evaluate systematically the clinical effectiveness and safety of Danhong injection (DI) and Salvia miltiorrhiza injection (SMI) in the treatment of cerebral infarction. Methods: A literature search was conducted for retrieving randomized controlled trials… read more here.
Keywords: medicine; injection salvia; danhong injection; injection ... See more keywords
Systematical Identification of the Protective Effect of Danhong Injection and BuChang NaoXinTong Capsules on Transcription Factors in Cerebral Ischemia Mice Brain
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DOI: 10.1155/2020/5879852
Abstract: Cerebral ischemia has led to a high rate of both disability and mortality with massive healthcare costs. Although transcriptional regulation is typically mediated by different combinations of TFs, a combined regulatory unit to synergistically activate… read more here.
Keywords: medicine; transcription; cerebral ischemia; buchang naoxintong ... See more keywords
Effect of Danhong injection on prognosis and inflammatory factor expression in patients with acute coronary syndrome during the perioperative period of percutaneous coronary intervention: A systematic review and meta-analysis
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DOI: 10.3389/fcvm.2022.1029387
Abstract: Objectives In China, Danhong injection (DHI) is recommended by expert consensus and is widely used in the perioperative management of patients with acute coronary syndrome (ACS). This study investigates the effect of perioperative DHI administration… read more here.
Keywords: meta analysis; danhong injection; effect; dhi ... See more keywords
A Defined Combination of Four Active Principles From the Danhong Injection Is Necessary and Sufficient to Accelerate EPC-Mediated Vascular Repair and Local Angiogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01080
Abstract: Many compounds in Chinese medicine formulae, including Danhong injection (DHI) formulae, are capable of stimulating angiogenesis and promoting vascular repair, but their chemical basis and action mechanisms remain poorly defined. The aim of this study… read more here.
Keywords: combination; angiogenesis; defined combination; necessary sufficient ... See more keywords