The Novel Cardiac Myosin Activator Danicamtiv Improves Cardiac Systolic Function at the Expense of Diastolic Dysfunction In Vitro and In Vivo: Implications for Clinical Applications
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DOI: 10.3390/ijms24010446
Abstract: Recent cardiotropic drug developments have focused on cardiac myofilaments. Danicamtiv, the second direct myosin activator, has achieved encouraging results in preclinical and clinical studies, thus implicating its potential applicability in the treatment of heart failure… read more here.
Keywords: cardiac systolic; myosin activator; diastolic dysfunction; danicamtiv improves ... See more keywords