Dantrolenbevorratung in Anästhesie und Intensivmedizin in Deutschland
Sign Up to like & getrecommendations! Published in 2017 at "Der Anaesthesist"
DOI: 10.1007/s00101-017-0335-z
Abstract: ZusammenfassungHintergrundDas Krankheitsbild der Malignen-Hyperthermie(MH)-Krise ist eine potenziell tödliche Komplikation in Anästhesie- und Intensivmedizin. Die einzige bekannte kausalpharmakologische Therapie ist die rechtzeitige Gabe von Dantrolen in ausreichender Menge. Internationale Anästhesiegesellschaften empfehlen als Initialdosis bei einer MH-Krise… read more here.
Keywords: die; und intensivmedizin; der; dantrolene ... See more keywords
UTILITY OF DANTROLENE FOR HYPERPYREXIA IN THE MANAGEMENT SARS-COV-2 INFECTION
Sign Up to like & getrecommendations! Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.07.862
Abstract: TOPIC: Critical Care TYPE: Medical Student/Resident Case Reports INTRODUCTION: Coronavirus Disease 2019 (COVID-19) continues to be a global pandemic with its management evolving as research continues to unveil innovative therapies. Dantrolene, approved in malignant hyperthermia,… read more here.
Keywords: covid patients; relevant relationships; case; dantrolene ... See more keywords
DANTROLENE INDUCES MITIGATION OF MYOCARDIAL ISCHEMIA-REPERFUSION INJURY BY RYANODINE RECEPTOR INHIBITION.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in thoracic and cardiovascular surgery"
DOI: 10.1053/j.semtcvs.2021.01.004
Abstract: The impairment of intracellular calcium homeostasis plays an essential role during ischemia-reperfusion injury. Calcium release from sarcoplasmic reticulum which is triggered by myocardial ischemia is mainly mediated by ryanodine receptors. Dantrolene sodium is a ryanodine… read more here.
Keywords: reperfusion; ischemia reperfusion; dantrolene; reperfusion injury ... See more keywords
Malignant Hypercompliance.
Sign Up to like & getrecommendations! Published in 2017 at "Anesthesiology"
DOI: 10.1097/aln.0000000000001597
Abstract: A T the University of Wisconsin, Madison, Wisconsin, in the 1970s, a circulating nurse was designated to maintain a list of all malignant hyperthermia (MH) family surnames taped to the inside of the swinging doors… read more here.
Keywords: anesthesia; ellis; dantrolene; two decades ... See more keywords
Drawing up dantrolene for the treatment of malignant hyperthermia: use of a drawing up spike to make the process easier and quicker
Sign Up to like & getrecommendations! Published in 2020 at "Anaesthesia"
DOI: 10.1111/anae.15044
Abstract: Malignant hyperthermia (MH) is an inherited disorder of the ryanodine receptors in skeletal muscle, triggered by inhalational anaesthetic agents and depolarising muscle relaxants. It is a rare and potentially fatal condition, which can bedifficult to… read more here.
Keywords: drawing dantrolene; treatment; malignant hyperthermia; dantrolene treatment ... See more keywords
Strategic Utilization of Dantrolene in a Case of Severe Acute Generalized Tetanus.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of pharmacy practice"
DOI: 10.1177/08971900231178429
Abstract: Tetanus is a life-threatening, vaccine-preventable disease caused by an endotoxin produced by Clostridium tetani. We report a case of severe tetanus in an adult male with a history of intravenous drug use. The patient presented… read more here.
Keywords: acute; case severe; tetanus; strategic utilization ... See more keywords
Relationship between HSPA1A-regulated gene expression and alternative splicing in mouse cardiomyocytes and cardiac hypertrophy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of thoracic disease"
DOI: 10.21037/jtd-21-1222
Abstract: Background Cardiac hypertrophy may be classified as either physiological or pathological. Pathological hypertrophy has a complex etiology and is genetically regulated. In this study, we used a mouse model of cardiac hypertrophy to explore the… read more here.
Keywords: cardiac hypertrophy; hspa1a; hypertrophy; expression ... See more keywords
Dantrolene inhibits lysophosphatidylcholine-induced valve interstitial cell calcific nodule formation via blockade of the ryanodine receptor
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1112965
Abstract: Calcific aortic valve disease (CAVD), a fibrocalcific thickening of the aortic valve leaflets causing obstruction of the left ventricular outflow tract, affects nearly 10 million people worldwide. For those who reach end-stage CAVD, the only… read more here.
Keywords: blockade; calcific nodule; nodule formation; dantrolene ... See more keywords
Molecular Aspects Implicated in Dantrolene Selectivity with Respect to Ryanodine Receptor Isoforms
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065409
Abstract: Dantrolene is an intra-cellularly acting skeletal muscle relaxant used for the treatment of the rare genetic disorder, malignant hyperthermia (MH). In most cases, MH susceptibility is caused by dysfunction of the skeletal ryanodine receptor (RyR1)… read more here.
Keywords: molecular aspects; dantrolene; ryr2 channel; ryanodine receptor ... See more keywords
Malignant hyperthermia in Mazovia Province – are we adequately prepared?
Sign Up to like & getrecommendations! Published in 2022 at "Anaesthesiology Intensive Therapy"
DOI: 10.5114/ait.2022.115348
Abstract: Background Malignant hyperthermia (MH) is a life-threatening syndrome caused by sudden skeletal muscle hypermetabolism in response to inhalation anaesthetics and depolarising relaxants. The estimated incidence of MH is between 1 : 10,000 and 1 :… read more here.
Keywords: mazovia province; anaesthesiology; malignant hyperthermia; dantrolene ... See more keywords