Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites
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DOI: 10.1080/00498254.2016.1204567
Abstract: Abstract 1. Finding and developing inhibitors of catechol-O-methyltransferase (COMT) from natural products is highly recommended. Daphnetin, a naturally occurring catechol from the family thymelaeaceae, has a chemical structure similar to several potent COMT inhibitors reported previously.… read more here.
Keywords: daphnetin; daphnetin phase; catechol methyltransferase; comt ... See more keywords